Development of Nano-Carbon Biosensors Using Glycan for Host Range Detection of Influenza Virus "2279

نویسندگان

  • Toshio Kawahara
  • Hiroaki Hiramatsu
  • Yasuo Suzuki
  • Shin-ichi Nakakita
  • Yasuhide Ohno
  • Kenzo Maehashi
  • Kazuhiko Matsumoto
  • Kazumasa Okamoto
  • Teruaki Matsuba
  • Risa Utsunomiya
چکیده

Nano-carbon materials are promising canidates for applications in high performance devices, including highly sensitive biosensors. We have developed a self-alignment process for nano-carbon field effect transistors (FETs), using a carbon nanowall (CNW)—a nano-carbon materials—to fabricate CNW-FETs. We measured the pH dependence of the device properties. The binding molecules are known to be key components for biosensors. We are concentrating on the development of an influenza virus sensor, because the influenza virus is a major public health problem and a highly sensitive sensor is urgently required. We estimated the size of detected molecules of glycan for influenza viruses using atomic force microscopy. The typical molecule size is around 1 nm, and this may be suitable for electronic detection using a FET structure.

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تاریخ انتشار 2016